The importance of semen leukocytes in HIV-1 transmission and the development of prevention strategies

M Cavarelli, R Le Grand - Human Vaccines & Immunotherapeutics, 2020 - Taylor & Francis
… the life expectancy of HIV-1 infected individuals; however, there … Indeed, virus-specific T cells
in the semen do not control … A dual chamber model of female cervical mucosa for the study …

[HTML][HTML] The role of innate immunity in natural elite controllers of HIV-1 infection

Y Shi, J Su, R Chen, W Wei, Z Yuan, X Chen… - Frontiers in …, 2022 - frontiersin.org
… of HIV infection, HIV-1-infected natural elite controllers are a … ), and maintain a CD4+ T
lymphocyte count at a normal level (>… shedding in the cervix of HIV-infected women, suggesting …

Human immunodeficiency virus infection promotes human papillomavirus-mediated anal squamous carcinogenesis: an immunologic and pathobiologic review

O Bushara, K Krogh, SE Weinberg, BS Finkelman… - Pathobiology, 2022 - karger.com
… contribute to CD8+ T lymphocyte exhaustion by upregulating … The anal canal mirrors the
milieu of the cervix, which is … immune cells may generate productive levels of the Tat protein. Tat …

[HTML][HTML] Comparison of the Biological Basis for Non-HIV Transmission to HIV-Exposed Seronegative Individuals, Disease Non-Progression in HIV Long-Term Non …

J Hokello, P Tyagi, S Dimri, AL Sharma, M Tyagi - Viruses, 2023 - mdpi.com
… T lymphocytes or CD8+ T-lymphocyte-mediated virus suppression. … from a group of HIV-1-infected
individuals. Furthermore, … known whether the high levels of virus-specific CD8+ T cells …

[HTML][HTML] Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques

AM Cadena, JD Ventura, P Abbink… - Nature …, 2021 - nature.com
… Low levels of viral DNA were also detected in the cervix, lungs… groups, the highest levels
of virus-specific T cell responses … If these findings translate to HIV-1-infected humans, they …

[HTML][HTML] Antiretroviral therapy interruption (ATI) in HIV-1 infected patients participating in therapeutic vaccine trials: surrogate markers of virological response

L Leal, C Fehér, V Richart, B Torres, F García - Vaccines, 2020 - mdpi.com
… The goal of therapeutic vaccination is to augment virus-specific … HIV-1 DNA concentrations
increased during ATI and then … carcinoma of the skin or low grade anal or cervical dysplasia); …

[HTML][HTML] Immune checkpoint inhibitors as potential therapy for reverting T-cell exhaustion and reverting HIV latency in people living with HIV

JM Benito, C Restrepo, J García-Foncillas… - Frontiers in …, 2023 - frontiersin.org
… cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), T-cell … disease parameters, restoring
virus-specific T-cell responses … immune reconstitution in HIV-1-infected patients on treatment…

[PDF][PDF] Natural killer cell phenotypic, functional, and nutrient transporter profiles during spontaneous control of HIV-1 infection in black South Africans

N Batohi - wiredspace.wits.ac.za
… inhibitory, mature profile with low levels of immune exhaustion … in reduced binding of KIRs
to HIV-1 infected cells. (Apps et al., … index against the antibody concentrations. Titrations were …

[HTML][HTML] Post-immune antibodies in HIV-1 infection in the context of vaccine development: a variety of biological functions and catalytic activities

A Timofeeva, S Sedykh, G Nevinsky - Vaccines, 2022 - mdpi.com
Content of these and similar Abs among HIV-1-infected … in some patients, such virus-specific
Abs may be polyreactive [… effect in decreasing cytotoxic T lymphocyte immunity. Since the …

[HTML][HTML] Herpes zoster in HIV-1 infection: the role of CSF pleocytosis in secondary CSF escape and discordance

L Hagberg, RW Price, H Zetterberg, D Fuchs… - PLoS …, 2020 - journals.plos.org
… with blood CD4+ T lymphocyte counts above the 200 cells per … , 2 for thoracic, 3 for cervical
and 4 for cranial nerve. Selected … We identified 25 HIV-1-infected individuals who underwent …